3 Esophageal Conditions and How They’re Treated

3 Esophageal Conditions and How They’re Treated

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The esophagus serves as a muscular tube that connects the throat to the stomach, allowing food and liquids to pass through during digestion. Several conditions can affect this organ, causing symptoms that range from mild discomfort to severe complications. Understanding these conditions and their treatment approaches helps patients recognize symptoms and seek appropriate medical care from a gastroenterologist.

Gastroesophageal Reflux Disease (GERD)

A gastroenterologist commonly sees gastroesophageal reflux disease, which occurs when stomach acid frequently flows back into the esophagus, causing irritation to the lining. Common symptoms include heartburn, regurgitation of food or sour liquid, chest pain, difficulty swallowing, and a sensation of a lump in the throat. Some patients experience chronic cough, laryngitis, or disrupted sleep due to nighttime symptoms.

Treatment approaches for GERD typically begin with lifestyle modifications. Patients may benefit from elevating the head of their bed, avoiding trigger foods such as spicy or acidic items, eating smaller meals, and maintaining a healthy weight. Smoking cessation and limiting alcohol consumption also help reduce symptoms.

Medical treatment often involves medications that reduce acid production. Proton pump inhibitors (PPIs) such as omeprazole and esomeprazole effectively decrease stomach acid production. H2 receptor blockers like ranitidine and famotidine offer another option for acid reduction. Antacids provide quick relief for mild symptoms. In severe cases where conservative treatments fail, surgical interventions may be necessary. 

Esophageal Stricture

Esophageal stricture involves the narrowing of the esophagus, which can result from scar tissue formation, inflammation, or other underlying conditions. GERD represents the most common cause, as repeated acid exposure leads to tissue damage and scarring. Other causes include radiation therapy, certain medications, and autoimmune conditions.

Patients with esophageal stricture typically experience progressive difficulty swallowing, starting with solid foods and potentially advancing to liquids. Food impaction, where food becomes stuck in the narrowed area, can occur. Weight loss and chest pain during swallowing are additional symptoms.

Diagnosis involves imaging studies such as barium swallow tests and upper endoscopy, which allow physicians to visualize the narrowed area and determine the extent of the stricture. Treatment focuses on widening the narrowed area through dilation procedures. Esophageal dilation uses specialized instruments to gently stretch the stricture, allowing improved food passage. This procedure may require repetition over time as strictures can recur.

Eosinophilic Esophagitis

Eosinophilic esophagitis is a chronic inflammatory condition characterized by the accumulation of eosinophils, a type of white blood cell, in the esophageal tissue. This condition often relates to food allergies and environmental allergens, affecting both children and adults. Children commonly experience feeding difficulties, vomiting, abdominal pain, and failure to thrive. Adults typically present with difficulty swallowing, food impaction, and chest pain. 

Diagnosis requires upper endoscopy with tissue biopsy, as the presence of elevated eosinophil counts in esophageal tissue samples confirms the diagnosis. Allergy testing helps identify trigger foods or environmental allergens. Treatment approaches include dietary modifications, medications, and environmental control measures. Elimination diets remove common trigger foods such as milk, eggs, wheat, soy, nuts, and seafood. 

Topical corticosteroids, such as fluticasone or budesonide, reduce inflammation in the esophageal tissue. These medications are swallowed rather than inhaled, allowing direct contact with the affected area. Systemic corticosteroids may be used for severe cases but are typically reserved for short-term treatment due to side effects. 

Find a Gastroenterologist

These three esophageal conditions require individualized treatment approaches based on patient symptoms, underlying causes, and response to therapy. Patients experiencing persistent swallowing difficulties, chest pain, or other esophageal symptoms should seek medical evaluation for proper diagnosis and treatment planning. Early intervention often leads to better outcomes and prevents complications associated with these conditions.

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